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This information is redundant for the closest neighbor method which is based on complete alignments.
All analyses based on complete alignments show high support values for the monophyly of the group containing M. intermedium, M. betonicae, and M. pinguiculae (Figs. 1, 3); this is an astonishing aspect: even though all of these species form their sori in the anthers they parasitise on different host families.
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The evolutionary conservation levels for human TFBS were determined based on complete genome sequence alignments [ 37] between the human genome and 16 other vertebrate genomes [ 38].
Phylogenetic grouping after alignment of the DTSsa and pTSsa transposon sequences based on complete or nearly complete DNA sequence [ 28] is shown in figures 1A and 1B.
In this paper, peak alignment for HiCEP electrophoretic data (Step 2) is performed using an algorithm based on complete linkage hierarchical clustering [ 20], though algorithms based on dynamic programming (DP) have widely been used for the purpose [ 21- 25].
Based on our alignments of complete gene sequences in bats, we identified two highly variable regions (exons 7 and 17).
Based on Multiple Alignments of Complete Sequences (MACS) 32 and 3D structures available in the SM2PH database, 33 MSV3d annotates each mutation with various parameters describing the physico-chemical changes induced by the amino acid modification, as well as the conservation of the mutated residue and its position relative to functional features in the available or predicted 3D model.
The identification of background conservation and reconstruction of the evolutionary history of each reference sequence is based on Multiple Alignments of Complete Sequences (MACS) (34), thanks to a modified version of the PipeAlign program (24) and to the MACSIMS (MACS Information Management System) software.
Alignments were performed iteratively and each sequence was refined based on alignments to make complete Or, Gr, and Ir sequences for A. cerana.
Bioedit 7.0 was used to conduct complete multiple alignment based on the complete nucleotide of cloned LMW-GS genes and other genes from GenBank.
2 Sequence similarity based on alignments of the complete sequences Additional gene fragments were identified 5' of the GI conserved region.
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