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Comparative genomic hybridization (CGH) which is based on competitive hybridization of amplified tumor DNA and normal DNA hybridized on normal metaphase slide was first developed by Kallioniemi et al. in 1992 to detect genomic imbalances in tumor cells [ 36].
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The microarray experiment design was based on competitive hybridizations of HAL-PDT treated cells vs untreated.
Under his proposal, Mr. Romney says, the government contribution would be based on competitive bidding.
Our pricing strategy will be based on competitive parity guidelines.
A method is described for HPV genotyping based on multiplex competitive hybridization (MUCH) combined with apyrase mediated allele-specific extension (AMASE).
Because microarray is based on probe-target hybridization, cross hybridization among probes from members of gene families could produce false-positive signals under some hybridization conditions.
Two nCounter probesets were excluded: one for poor predicted hybridization specificity, and one based on hybridization failure.
Hybridization-based methods include northern blot hybridization and those based on liquid-phase hybridization, such as nuclease protection assay.
This is partly based on DNA hybridization studies that show it to be allied to the tanagers (Bledsoe 1988).
Studies based on DNA hybridization suggested years ago that the then-current classification of birds was incorrect in many ways.
For these purposes, an electrochemical sensing system was developed based on detecting hybridization.
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