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In addition, the best 3D-QSAR model presented higher predictive ability (R2train = 0.958, R2test = 0.852, Q2LOO = 0.734) based on comparative molecular field analysis (CoMFA).
Two 3D-QSAR models, which based on comparative molecular field analysis (CoMFA) and comparative molecular similarity analysis (CoMSIA) methods, were established.
Based on comparative molecular dynamics simulations using explicit and implicit solvent models, we studied the dynamic properties of both protein and water.
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In most respects, the "molecular tree" for arthropods is readily interpreted in the context of current and classical homology schemes based on comparative anatomy; molecular and morphological estimates of phylogeny are in good agreement.
Based on comparative analyses of rDNA sequences and molecular karyotyping of Lachancea species, the yeast appears to have eight chromosomes [ 13], and its preferred growing temperature is 25-37°C 25-37°C
The biological reasons at the basis of this molecular evidence deserves further work based on comparative genomics diversity studies among T. aestivum, T. durum, T. dicoccum and particularly the wild emmer T. dicoccoides.
This hypothesis based on comparative domain analysis may serve as a pointer towards further molecular studies.
Here, we present a detailed molecular cytogenetic map for the duck based on comparative FISH mapping of 155 chicken BACs, which revealed several hitherto undescribed intrachromosomal rearrangements.
Further studies, including studies based on comparative gene profiling strategies, are required to better define the likely complex molecular machinery that links KRIT1 to FoxO1 functions.
Future molecular typing and epidemiological studies should be aimed at providing genotyping data based on comparative genomic analyses.
In this perspective, the identification of the most likely compensatory partner for each mutation was initially based on comparative sequence data and subsequently complemented with 2D and 3D structural analyses to allow the recognition of the molecular basis of interactions.
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