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P. zucineum is phylogenetically closest to C. crescentus based on comparative genome analysis.
This is in accordance to the phylogeny of these fungi based on comparative genome analyses showing in Figure 3.
Based on comparative genome analysis across multiple organisms, protein families have been identified containing domains for which minimal functional annotation is available.
The possibility that genome rearrangements such as deletions or amplifications are responsible for the differential motility phenotype has been ruled out based on comparative genome hybridization and fingerprinting.
Indeed, computational-experimental screens based on comparative genome analysis identified seven different ncRNAs in the marine cyanobacteria Prochlorococcus and Synechococcus [ 8] which were called Yfr1-7 for c Y anobacterial F unctional R NA.
To date, several models for the evolution of genomes have been proposed based on comparative genome studies of model organisms [ 45- 47], but little attention has been focused on the structural evolution of duplicated gene families.
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In addition, they are one of the very few recipients currently funded by the Natural Science Foundation of China (NSFC) to work on SB-related projects, including a project on minimal genome research that is based on comparative genomics and large-scale deletion of genome fragments.
We characterized a high copy Stowaway family MITE, named as BRAMI-1, in three Brassica crops and showed its putative role in the evolution of the highly duplicated Brassica genome based on comparative genomics analysis.
Most of these genes contain smaller ORFs and were found to have orthologs in C. albicans which have been just recently added to the genome based on comparative genomic studies of eight Candida species by Butler and colleagues [ 41].
We are particularly interested in assessing niche adaptation and in investigating the pathogenic potential of the strain analyzed based on comparative genomics against other complete genomes within the SBSEC.
To assess gene loss based on comparative genomics, the Micromonospora sp. L5 genome was used as the reference sequence for the pair-wise RSD test of orthology in 27 representative Actinobacterial genomes, including both Salinispora spp. Four of 430 genes with predicted orthologs in at least 24 of the 27 genomes are absent in both Salinispora sequences (Additional file 2).
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