Sentence examples for based on common variants from inspiring English sources
The genetic architecture of schizophrenia (SZ) is based on common variants identified by Genome Wide Association Studies GWISS) and on rare variants.
Everyone will get a score that estimates the liability to lung cancer based on common variants.
Prediction of disease risk based on common variants and clinical profiles is described for the Caucasians in [ 7].
Genome-wide association studies (GWAS) based on common variants have been the dominant approach to achieve this objective [ 1].
To this end, we simulated a large dataset and constructed risk models based on common variants for increasing values of the baseline AUC.
This method, called the RNA Variant Boosting (RVboost), is a ranking machine to (a) train a model based on common variants in HapMap and (b) rank the variants accordingly.
Genome-wide association studies based on common genetic variants have identified a number of loci at compelling levels of statistical support (6– 10).
As hypothesized, this study found that ADHD polygenic score, based on common genetic variants previously found to be associated with risk of a clinical diagnosis of ADHD, was also associated with ADHD traits measured at ages 7 and 10 years in the general population.
Only about 5 10% heritability was found based on common disease common variant (CDCV) model.
Our finding of significant evidence for such a convergence underscores our contention that it is premature to dismiss the contribution of SNP variation, but more importantly, it begins to provide evidence that genome-wide studies of ADHD, based on common or rare variants, are likely to inform processes of relevance to pathophysiology.
