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The results show that hypotheses based on coalescent theory can be useful to reconstruct historic biogeographical events of oceanic islands in a range of different organisms provided that the sample design is adequate and enough genetic resolution is present.
We investigated the demographic history of HIV-1 subtype A and B in Albania by using a statistical framework based on coalescent theory and phylogeography.
Conversely, algorithms based on coalescent theory can be used to estimate species boundaries (e.g. [29]), but, among other intricacies, these rely on multi-locus sequencing [30 491] and can hardly be applied to environmental samples and to data that are only available as accessions in public databases.
An approach based on coalescent theory was also used to estimate the demographic history of lineages within C. aspersum.
Methods based on coalescent theory enable estimation of both current and past population sizes directly from genetic data.
Firstly, the likelihood method based on coalescent theory developed by McVean et al. [ 21] was used together with their likelihood permutation tests that test for statistical significance.
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Values of Nem ranged from 0.5 to 3.4 based on FST (Table 2) but were <1 among all populations based on coalescent migration estimates (Table 3).
For the DIND test, an approach based on coalescent simulations was also applied to assess statistical significance.
Expected number of alleles for Ne = 10 000 is approximately 10.5 based on coalescent simulations (Hoban et al. 2013c).
Many of the likelihood approaches mentioned above are based on the coalescent theory (K ingman 1982; G riffiths and T avare 1994).
Methods based on the coalescent theory trace the ancestral genealogy of a sample rather than modeling changes of gene frequencies in the population as a whole.
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