In the past and to some extent today, drug development in psychiatry deviated from step one in that serendipity usually based on clinical observation lead to small proof of principle trials, animal studies, and then to rational medical chemistry efforts [ 18], viz. the progression from imipramine to fluoxetine.
Included is knowledge of the preparation required for individual procedures, and of the principles of referral based on clinical history and clinical examination.
During case presentations students, interns and residents improve knowledge based on clinical experience, and learn the medical language, professional principles, traditions and values.
The NHS constitution's principle of 'access to services being based on clinical need' 23 is clearly not being applied to the critically injured before they reach hospital.
The principles of intensive, prolonged therapy were recommended in the late 1950s based on clinical experience [ 7, 8].
Major principle care for children with cardiogenic shock is primarily based on clinical and echocardiographic assessment.
Willie Rennie, the Scottish Liberal Democrat leader, said there was no threat in the UK to any of the basic NHS principles, which encompassed a health service free at the point of delivery, based on clinical need, and universally available.
When Bevan founded the NHS he said it would be based on the principles that it would meet the needs of everyone, be free at the point of delivery and be based on clinical need, not ability to pay.
With limited trial data available, this review proposes practical modifications to the usual pre-Ramadan antidiabetic regimens that are based on pathophysiological principles, clinical trial evidence (where available), expert opinion, and extended practical experience.
Based on biologic and clinical principles, instrumentation and obturation should not extend beyond the apical foramen.
