Sentence examples for based on clinical observation from inspiring English sources
In the past and to some extent today, drug development in psychiatry deviated from step one in that serendipity usually based on clinical observation lead to small proof of principle trials, animal studies, and then to rational medical chemistry efforts [ 18], viz. the progression from imipramine to fluoxetine.
This biomarker signature enabled superior pretreatment classification of response in three ethnically diverse cohorts, in comparison with a theoretical benchmark based on clinical observation and previous experience in population-based cohorts (one-third of patients no response, one-third of patients partial response, and one-third of patients good response).
No statistically significant difference was observed between the response rates (based on clinical observation and resolution on EEG when available) of patients put on either ACTH or Vigabatrin therapy initially.
Overall physician satisfaction increased by 34%and29%9% (based on clinical observation) for patients who were treated previously with calcium-based binders and sevelamer HCl, respectively, after 12 weeks of treatment with lanthanum carbonate.
Samani (2005) designed FPC Model based on clinical observation, family interview and experimental data.
Physical therapists completed the GNEM-FAS based on clinical observation and subject interview.
The Nu-DESC test was designed to be administered by a bedside nurse based on clinical observations in their routine practice, while only absorbing one minute of their time, on average.
Furthermore, biomarker adaptive designs can be applied in one clinical study to identify the most suitable target subgroup, based on clinical observations or known biomarkers, and to evaluate the effectiveness of the treatment in the patient subgroup [ 11– 15].
