CEAP classification symptoms are based on clinical signs, etiologic classification, anatomic distribution and pathophysiologic dysfunction, and include: leg pain, swelling, leg-related sleep problems, skin discoloration, cosmetic appearance, activity limitation, and emotional distress [ 5, 13].
Based on clinical and immunological classification, the Brazilian guidelines recommend dual or triple therapy for children.
In future studies, we will study more clinical samples based on clinical and histopathological classification to find out the relationships between the expression level of ABCG2 and other CSC markers and the prognosis and clinical implications of ACC patients.
In a subset of hematologic malignancies, specific mutations and translocations have been used in classification but otherwise tumor classification is based on clinical, histological, and pathological parameters.
OI type was classified according to Sillence et al. (1979), which is a classification based on clinical, radiographic, and genetic characteristics.
IP-10 plasma levels were compared between LS and healthy controls, as well as within LS between active and inactive disease (activity classification based on clinical parameters).
Cancers were staged according to the TNM version 7 classification, based on clinical, imaging and pathological information (Sobin et al, 2009).
ID stages were judged according to the Wilkes and Bronstein classification based on clinical symptoms and pre-operative magnetic resonance imaging.
The Radiation Therapy Oncology Group (RTOG] recursive partitioning analysis (RPA) classification based on clinical factors (Karnofsky performance status, age, and control of extracerebral disease) is a major prognostic indicator for patients with brain metastases [ 13].
