Sentence examples for based on cell viability from inspiring English sources
71 Discovery and development of new metal-based anticancer agents is largely based on cell viability assays (IC50 values), intracellular accumulation and distribution studies.
Cytotoxicity of conjugates was assessed in MDA-MB231 and SKBR3 cancer cells based on cell viability by XTT assay and flow cytometric analysis.
Three specific formulations were chosen for further study based on cell viability and mechanical integrity assessments: 4% 90 kDa, 2% 250 kDa and 3% 250 kDa CMC.
(F) Primary hepatocytes from normal mouse livers were treated with exosome-mimetic NVs from wild-type mice- or Sphk2−/− mice-derived primary hepatocytes at a final concentration of 100 μg/ml for 48 h, and cell proliferation was assessed based on cell viability using MTT assays.
Cytotoxicity was rated based on cell viability (after 48 h) relative to controls as: non-cytotoxicity >90% cell viability, slightly cytotoxicity¼ 60 90% cell viability, moderately cytotoxicity¼ 30 59% cell viability, and severely cytotoxic ¼ <30% cell viability (Badole et al. 2013; Dahl et al. 2006).
Dosing was based on cell viability.
From the MTT assay results, it is observed that the biocompatibility of the nanoparticles, based on cell viabilities, can be enhanced by increasing the r-ratio, regardless of the stirring rate.
On the day of harvest the required volume of the dead cell stock was calculated based on cell density and viability measurements of both the harvest material and the dead cell stock, obtained using a ViCell™ (Invitrogen, Paisley, UK).
Consistently, all the three Cas mutants along with wt Cas effectively mediated MG132-induced apoptosis, based on cell death ELISA and cell viability assays.
Lung cell viability was determined based on cell distribution on FSC-SSC dot plots and by tripan blue exclusion, which gave similar results.
The cytotoxicity of the probiotic supernatants on the four cell lines based on the cell viability assay is shown in Figures 3 and 4. Based on the obtained cytotoxicity index (CI%) plots, the IC50 of the anticancer drug bleomycin was shown to be 9.31% for HDFn and 4.77% for THP-1 cells.
