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This represents the first example of a fluorescent compound labeling cells based on cell surface carbohydrate structures.
The chimeric monovalent Fab fragment of the DN30 monoclonal antibody (MvDN30) has an odd mechanism of action, based on cell surface removal of Met via activation of specific plasma membrane proteases.
Based on cell surface staining, there was no expression on T-cells and significant expression on B-cells (Fig. 9A).
A population of cells can also be purified based on cell surface marker expression and transplanted into lipodystrophic mice to reconstitute fat depots [11].
Recent advances in the identification of specific neural cell types based on cell surface and intracellular markers, using flow cytometry, have lead to detailed characterization of neural stem and progenitor cells, as well as their down-stream progeny.
To help organize the data that are based on cell surface marker intensities, we reviewed the top 20 intensity variables with differences greater than 15% between the autism and control groups and had adjusted p-values<0.05.
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The minority B-1 B-lymphocyte population is classified into B-1a and B-1b subsets based on cell-surface CD5 expression.
As shown in Figure 6E, pharmacodynamics effects based on cell-surface CD69 expression on B cells (B220+), as judged by ex vivo stimulation with anti-IgD, were consistent with pharmacokinetics analysis of compound exposure.
The utility of the sensor platform in rapid sensing of mammalian cells based on cell-surface glycosylation pattern was demonstrated first using glycomutant cells featuring different glycosaminoglycans (GAGs) as part of the cell surface proteoglycans.
All these methods introduce assumptions and biases that might result in selective loss of certain populations of cells based on cell size, surface antigen expression or biophysical properties.
First, we have employed two different purification schemes, composed of three levels of cell separation based on cell density and surface expression to remove most leukocytes, platelets and reticulocytes, to obtain the mature erythrocytes used for expression analysis.
More suggestions(15)
based on cell averaging
based on cell permeabilization
based on cell morphology
based on cell tracking
based on cell aggregation
based on cell adhesion
based on cell replacement
based on response surface
based on cell overlapping
based on cell seeding
based on cell biology
based on cell lineage
based on cell proliferation
based on cell radius
based on cell number
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