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This classification is based on cell of origin, maturity, morphology, immunophenotype, genetic and clinical features [ 4].
Oosterhuis and Looijenga have proposed classification of GCTs into five distinct entities based on cell of origin, histology, genomic imprinting status, age at and location of clinical presentation, and chromosomal constitution [ 2].
There are three subtypes of such tumors based on cell of origin: stromal luteoma arising from ovarian stroma, Leydig cell tumor arising from Leydig cells in the hilus, and steroid cell tumor (not otherwise specified, or NOS) when the lineage of the tumor is unknown [ 1].
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This biosensor is based on cells of a specifically modified Saccharomyces cerevisiae strain immobilized in alginate beads.
A first ranking of the sites is obtained based on cells of residence of the users at a geographical scale of 100 by 100 kilometers.
The numbers of counted cells were expressed as % observations based on cell distribution of the 200 counted cells multiplied with the total number of cells for each mouse.
Thus, the aim of the research was to establish an in vitro source of biologically active methoxylated isoflavones based on cell cultures of C. subternata.
Cytotoxicity was based on cell numbers of each treatment group counted by Coulter Counter and expressed as percent of cell survival compared to the untreated control.
However, these hypotheses are solely based on cell morphology of the parasperm and require experimental support [23], [50].
In fact, miRNA signatures related with the molecularly defined subgroups of DLBCL based on the cell of origin have been found by different groups.
Sometimes classification is based on the cell of origin, whereas in other cases it is based on the tumour's microscopic architectural pattern or gross appearance.
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