Sentence examples for based on cell cycle from inspiring English sources
Likewise consistent with the notion that the antiviral activity of JMN3-003 is not based on cell cycle arrest itself, virus inhibition was not restricted to the context of immortalized, rapidly dividing tissue culture cell lines but extended with equal potency to primary human PBMCs.
Importantly, SR and IR cells were indistinguishable from each other based on cell cycle distribution/proliferation characteristics.
We also provided cell classification based on cell cycle states and analyzed co-expression network modules of HeLa S3 cells.
To investigate the interplay between macrophage apoptosis and ER stress responses, we first confirmed that HBHA induced apoptosis, based on cell cycle analysis using flow cytometry.
Geminin [ 12], TopoIIα [ 34, 35] and Cdc7 silencing or CKIε overexpression had minimal effects on S-phase progression or DNA replication based on cell cycle and bromodeoxyuridine incorporation analysis (data not shown).
Two possible combination approaches have been proposed to solve this problem: a pure sequential strategy, in which chemotherapy is followed by maintenance EGFR TKI treatment [ 18, 19], and an intercalated administration strategy based on cell cycle-dependent cytotoxicity, which was supported by the results of preclinical and preliminary clinical studies [ 12– 16].
When clustering cells based on cell-cycle genes only, we found that 2i cells separate into two groups: one with high expression of G2 and M genes and a second with lower expression of these genes.
We also used transcription factor (TF DNA binding data (Chip-chip) and protein phosphorylation data to construct a local cell cycle regulation network based on potential cell cycle related gene set we predicted.
Y-axis scale indicates % cell-cycle progression based on cell length.
Compounds from group III could be classified into two distinct groups based on their cell cycle profiles in leukemic and normal cells.
In the numerical simulations, we compute the time evolution of the cells in Eq (1) using the longer time scale based on the cell cycle length, and at each time step we solve the quasi-steady states of the molecules in Eq. (3) for computational efficiency [ 23].
