Sentence examples for based on candidate miRNAs from inspiring English sources

In this analysis, samples were classified using K-means clustering based on candidate miRNAs expression levels into two groups which were defined as luminal-A trend or basal-like trend according to the proportion of two breast cancer subtype samples.

First, using hierarchical clustering based on the candidate miRNAs expression, we successfully separated the 19 samples of cancer tissue and 6 normal samples into discrete groups.

To identify candidate precursor from false positives, we used a sequence and structural feature filter designed based on A. thaliana miRNAs and their precursors.

Based on miRNA-AFLP technology, the miRNA-SRAP marker technique was performed to enrich miRNA markers.

To recover the putative miRNA candidate, the potential precursors were screened based on the plant miRNAs prediction criterion as described by Meyers et al. [ 34].

In conclusion, we report a strategy for the rational selection of drug repurposing candidates based on miRNA-TF FFLs.

Therefore, we needed the Sequence & Structural features filter devised based on known miRNA features, to distinguish authentic candidates from false positives.

MiRDeep is based on the miRNA biogenesis probabilistic model, and makes use of the information of position and frequency of candidate mature sequences in the miRNA precursors secondary structure.

miRDeep2 takes as input the position and frequency of reads aligned to the genome ("signature") with respect to a putative RNA hairpin and scores the miRNA candidate employing a probabilistic model based on miRNA biogenesis [ 26].

Based on this, candidate was selected.

In the second step, the expression profile filtering was based on miRNA expression pattern using the abundance of the miRNA candidates in each library and the distribution of reads mapped to a candidate pre-miRNA according to Meyers et al. relaxed criteria [ 42].