Sentence examples for based on biological parameters from inspiring English sources
Information on time since seroconversion, which can be obtained in cross-sectional surveys, could be based on biological parameters that change with time since infection (such as CD4 count, total lymphocyte count, or viral load), clinical assessment (such as screening for HIV-related diseases that indicate late-stage HIV disease [40]), and screening for ART (through a question or laboratory test).
One additional filter that may improve the detection of functional coevolution between amino acid sites is that based on biological parameters.
The activity of VPA in patients with solid tumours may be improved by patient selection based on biological parameters (e.g. HDAC2 overexpression) or by the combination of VPA with drugs that may act synergistic with HDAC inhibitors.
Finally, there are no criteria or guidelines to start therapy based on biological parameters and more clinical studies are needed to determine the optimal conditions for a successful HIV-2 therapy.
To combat this, the parameters could be weighted based on biological importance, giving more weight to parameter dimensions deemed important by the experimenter.
Model parameters based on biological literature are summarized in Table 1.
A set of adequately selected parameters based on biological processes may deliver accurate all-round tumor classification for grouping of uniform tumors for treatment allocation, prediction of treatment response or distinction of patient groups with a different prognosis.
1Db: Functional modules based on biological process (one-dimensional modules).
To mimic the behaviour of the real biological system, model parameters have to be tuned based on biological observations.
In our previous study, we constructed a dynamic simulation model of E. coli based on biological knowledge and reproduced the experimental cultivation results by parameter fitting [ 10].
One possible avenue for further analysis of this vast parameter space is by creating groups defined by different behavior classes based on biological and dynamical information [ 37, 39].
