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Gibbs and Weiller, based on bioinformatics results of the Rep protein amino acid sequence of circovirus and Nanoviridae, provided a hypothesis of the origin and evolution of circovirus.
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Moreover, no information is available about the dominant or recessive inheritance of the mutation in humans and theoretical predictions based on bioinformatics approaches give contradictory results as to whether V234I mutation has a damaging effect on the function of the protein (van Blitterswijk et al., 2012; Ingre et al., 2013).
Several sRNAs were annotated in genomes based on bioinformatics predictions, but for the first time our results provide support at the transcriptional level.
Based on bioinformatics and homology modelling analyses, E449 was revealed to be the potential nucleophilic residue.
Another 12 putative phosphorylation sites were also found based on bioinformatics predictions and previous reports.
B-cell epitopes were predicted on structural proteins of WNV and JEV based on bioinformatics tools.
Based on bioinformatics analysis, 10 antigenic peptides derived from the S protein sequence were selected and synthesized.
A model of tirandamycin biosynthesis was proposed based on bioinformatics analyses, gene inactivation experiments and intermediates isolated from the mutants.
These findings, based on bioinformatics analyses, can be conducted in further experimental analyses in cancer therapy and vaccine design.
Based on bioinformatics analysis, a soluble, and non-allergic protein with 35.405 kDa molecular weight was designed.
Porcine miRNAs were identified based on bioinformatics and based on comparisons to corresponding human miRNA sequences.
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