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This resulted in 41 distinct bioinformatically derived classes, containing at least one CpG, based on bioinformatic attributes [for the distribution of CpG loci by bioinformatically derived class, see Supplemental Material, Table 2 (http://dx.doi.org/10.1289/ehp.1103927)].
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Based on bioinformatic analysis, a putative biosynthetic pathway is proposed.
As this prediction is based on bioinformatic analyses and the experimental data are still lacking.
Here, two degenerate primer sets (HEV and HRVC) were designed based on bioinformatic analyses.
The majority of the identified proteins were located in chloroplast and cytoplasm based on bioinformatic analysis.
To verify our hypothesis, based on bioinformatic predictions, functional in vitro studies were performed.
The four mammalian homologs fall into two groups based on bioinformatic analysis: WIPI1/2 and WIPI3/4 [16,17].
The list of genes was assigned based on bioinformatic research and the analysis of literature data.
Future studies will focus on the investigation of pathogenetic pathways based on bioinformatic modelling of their involved genes.
However, based on bioinformatic and biochemical evidence, we suggest that the SROs do not possess PARP or mART activity.
Based on bioinformatics and homology modelling analyses, E449 was revealed to be the potential nucleophilic residue.
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