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SI allows a pistil to recognize and reject self-pollen prior to fertilization, based on biochemical interactions between pollen and pistils [ 46, 47].
Our simplified model of a self-sustained polyadenylation of αCaMKII-mRNA is based on biochemical interactions between a plasticity related kinase αCaMKII and its translational regulator CPEB1 through a positive feedback.
Although genetic evidence for MAGUK-dependent clustering of NMDA receptors is strongest, and consistent with a model wherein MAGUKs traffick NMDARs to the membrane [ 7, 8], the evidence for scaffolding or trafficking of non-NMDA ionotropic glutamate receptors by MAGUKs is largely based on biochemical interactions and overexpression [ 9- 12].
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This technique is based on biochemical interaction of antigen-antibody or probe DNA-target DNA hybridization.
We think that this is a pedagogically important moment in the module as we get a chance to recall the results from our initial class discussion (based entirely on biochemical interactions) to determine the state of the operon (ON or OFF) based on the presence or absence of external glucose and external lactose.
We began with a standard molecular model of signal transduction based explicitly on biochemical interactions of network proteins.
Based on biochemical and immunological experiments, all four interactions were proposed to be relevant for MAG inhibition, but the relative contribution of each interaction remained elusive.
To predict the dynamic behavior of components in the gene network models, we constructed mathematical models based on biochemical reactions (e.g., the dynamics of interactions with the promoter, protein synthesis, decay of the components).
Although the bulk of the claims based on biochemical analysis are well supported by genetic studies, direct evidence of interactions and covalent modification of endogenous proteins would strengthen the paper.
Mathematical descriptions of interactions of the mechanistic parts of the pathways were modeled based on biochemical reaction equations.
Most of the mainstream practitioners of addiction treatment believe addiction is based on biochemical reactions to taking drugs, drinking alcohol or smoking tobacco.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com