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Instead, based on biochemical data on the effect of mutations on NAT2 acetylator activity, it is plausible that in the ancestral genetic background, all slow-causing mutations had an equivalent effect on phenotype and fitness.
A fermentation pathway has been proposed based on biochemical data [ 34].
Additionally, based on biochemical data and the structures, the authors propose a model for SRP engagement in eukaryotes.
The four risk prediction systems based on biochemical data are excellent at predicting mortality of acutely admitted medical patients.
Based on biochemical data, translocation through the outer membrane is believed to be mediated by voltage-dependent anion channel (VDAC) isoforms in higher eukaryotes.
Based on biochemical data estimated 40 100 ComGC monomers assemble into a pseudopilus, with each monomer contributing ∼1 nm to the length of the fiber 7.
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Using computer-generated synthetic data and some real data, we have demonstrated that BioCluster has high accuracy in clustering and identifying enterobacterial species based on biochemical test data.
On the other hand, for systems based only on biochemical data, interobserver or intraobserver variation is virtually eliminated.
We performed the present study with the objective of validating existing risk stratification systems that predict mortality for medical patients based solely on biochemical data.
Based on biochemical and structural data (i.e. the excess of NADPH over E1 and the different crystal structures for the apo-, holo- and ternary form) we hypothesized 17β-HSD1 to follow a five-step preferential pathway in vivo.
It has recently been proposed, based on biochemical and biophysical data, that the Isu1-interacting surface of yeast frataxin encompasses the iron binding sites, thereby positioning frataxin for iron delivery to Isu1 close to the Fe-S cluster assembly site [37].
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