Sentence examples for based on binding of from inspiring English sources
The authors' original observation – that the interdomain linker became sequestered from proteolysis concurrent with a shift to a higher molecular weight complex – led them to a model for BiP oligomerization that is based on binding of the linker of one monomer to the substrate-binding cleft of another monomer, to form a concatenated oligomer.
Blood cells, of which lymphocytes are one type, are commonly characterized by flow cytometry based on binding of fluorescently labeled antibodies to these markers (e.g., anti-CD x antibody will provide characteristics such as CD x +, CD x –, or CD x high, CD x low, or CD x dim for intermediate expression levels of marker x ).
Suppressive effect of regucalcin on nuclear DNA fragmentation may be partly based on binding of Ca2+.
The other key mechanism is based on binding of YAP to the PPXY motif on p73.
The method used is based on binding of the viral particles to an anionic exchange membrane adsorber (MA) followed by UF of the eluted purified particles.
Cellulosomes in cell-free broth were isolated from fermenting cultures using the affinity digestion method [ 44], which is based on binding of cellulosomes to amorphous cellulose.
"These drugs are more fragile because even the newer versions are still based on binding to different combinations of enzymes," says Dale Boger, a chemical biologist at the Scripps Research Institute.
Peptides were short chains of amino acids that can be designed based on binding sites of proteins, screened into specific sequences, and finally synthesized with chemical methods.
Based on binding patterns of Hsp70 antibodies that detect different epitopes in the ATPase and the C-terminal substrate binding domain, the orientation of Hsp70 in Gb3 containing CRMs appears to be identical (unpublished observation).
Our design rationale was to achieve tumor cell-specific capture patterns based on binding preferences of the tumor cells to the three antibodies (aEpCAM, aHER-2, and aPSA).
Microdosimetry was calculated based on binding and retention kinetics of 211At to the cells, as well as cellular and nuclear diameters.
