Sentence examples for based on binding affinity from inspiring English sources

Finally, 14 compounds were obtained based on binding affinity scores and interactions with protein active site residues.

Although numerous methodologies have been proposed for drug-target screening strategies based on binding affinity [7, 8], there are no efficient computational tools available for the accurate estimation of the drug uptake profiles from the point of the molecular structures.

A plausible mechanism of immune mediated diabetes based on binding affinity and peptide kinetics is discussed.

For example, xeno-estrogen compounds are typically compared with estradiol based on binding affinity strength.

In other recent work[ 15] several mutants to modulate the ubiquitin system have been identified based on binding affinity.

In our study, this score was based on binding affinity information for fixed sequences starting at the given base pair.

It is therefore difficult to envisage CyP-D selectivity based on binding affinities alone.

This is expected since the copy number of the majority of genes in DNA should be the same, and the signal intensity of DNA hybridizations is based more on binding affinity and the size of the bound DNA fragments since more label will be incorporated in larger fragments.

It is likely, however, that HiR7.8 will bind to androgen-dependent prostate cancer tissue from patients based on binding specificity and affinity similar to previously-identified molecules [ 58].

The docking results shown the rosmaricine derivatives bind influenza hemagglutinin with high affinity based on binding energy.

To further define the sequence requirement for PhoP binding, we tested the effects of single-base substitutions on binding affinity.