Sentence examples for based on binding ability from inspiring English sources

Phage display technology has been used for exploring novel peptides acting on GPCRs, but it is unclear whether the identified peptides functionally modulate targets because the technology selects peptides based on binding ability but not functional activity to targets.

This is due to the nature of phage display, whose peptides are screened based only on binding ability to targets, resulting frequently in simple binding peptides without any bioactivity (Chen et al. 2007).

The virtual screening abilities of AD4 and Vina were compared based on binding predictions between the members of two chemical libraries and HIV protease.

'Reverse chemical ecology' [ 26, 27] is a new concept for screening of attractants based on the binding ability of OBPs to test compounds rather than going through series of behavioural bioassays.

These results indicate the specificity of the Erb-hcAb-dependent cell-mediated cytolytic activity, clearly based on both binding abilities of the immunoagent: (i) to the cognate receptor with its antigen binding sites; (ii) to natural killer cells with its Fc effector domain.

Based on its SH3 binding ability, SYNJ1 was initially identified as interacting with Grb2 [ 1].

The cell-specific peptide TPS (TPSLEQRTVYAK) has been proposed as a potential candidate for fabricating tissue engineering scaffolds based on its ability of binding to human endothelial progenitor cells (EPC) with high affinity and specificity.

A-kinase anchoring proteins (AKAP) are a group of CTA which play important roles in sperm function and are classified based on their ability of binding to c-AMP dependent protein kinase A (PKA) II.

The family of insulin-like growth factor-2 mRNA-binding proteins was identified based on their ability to bind to IGF-2 mRNA and thereby regulate its stability and translation, which was verified in our study as well.

Using CCG, a library of 3D glycan shapes for the TF-containing glycans on the CFG array (v4.0) was created and searched for putative binding and nonbinding glycans, based on their ability to fit into the binding site.

The scavenger receptors were originally grouped based on their ability to bind acLDL as a ligand, even if this binding ability can have very low affinity [ 25].