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We can't fudge the numbers after the experiment has been done… That's because companies don't want to begin an expensive clinical trial based on basic research that is fundamentally flawed or just a product of randomness.
The university will appeal the ruling, which legal experts say could rein in inventors making similarly broad claims based on basic research.
Based on basic research and deep knowledge of methanotrophs, there are more possibilities to make methanotrophs become important and universal industrial microorganisms (Jiang et al. [2010]).
Drug development is now based on basic research findings, such as the effects of over-expression or deletion of genes encoding novel proteins or enzymes in specific in vitro systems.
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Recently, based on basic and clinical research indicating a greater potential for plastic changes in the brain, approaches directed toward functional restoration are becoming increasingly popular.
Thus this trial will examine an integrated intervention based on basic cognitive and behavioural research in a sample with a range of severity of alcohol use disorders.
But, we must remember that all clinical and patient-related research is based on basic science.
The purposes of this study were to develop classroom assessment system in Mathematics based on basic education curriculum 2008 approaching participatory action research, and to evaluate the system.
Based on current basic research, TAMs that have differentiated into the M2 phenotype are believed to be intimately involved in angiogenesis, immunosuppression, and activation of tumor cells.
Based on early basic research regarding the role of PD-1 in the negative regulation of T-cell responses (which can render them ineffective in an anti-tumor response), research efforts have been focused on blocking the interaction of PD-1 with its two ligands PD-L1 and PD-L2, primarily for cancer treatment but also for other immunotherapeutic applications.
Based on mechanistic basic research, it is now clinically and experimentally well established that stroke induces immunodepression through complex mechanisms, contributing to these post-stroke infections (Chamorro et al., 2012; Chamorro et al., 2007; Harms et al., 2008; McColl et al., 2009; Meisel et al., 2005; Prass et al., 2003).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com