Sentence examples for based on base pair from inspiring English sources

Catalytic RNAs might not have needed to evolve such a regulation mechanism due to the fact that their recognition strategy, which is based on base pair formation, provided sufficient specificity.

The limiting factor with such an adaptation is the fact that the suitable candidates need to have a recognition mechanism based on base pair formation in order to permit a rational design.

This measurement of single strandness has the advantage that it is based on base pair probabilities.

Going beyond LocARNA, which sparsifies based on base pair probabilities, SPARSE additionally sparsifies based on conditional probabilities of bases and base pairs within loops (Otto et al., 2014).

Oligomerization of the nucleo amino acids allows for the formation of rigid and well defined double strands with linear topology based on base pair recognition, stacking, and solvation.

These procedures calculate, based on base pair formation rules [ 45], the free energy values for the binding of the 3' end of the 16S rRNA with the region preceding each ORF at different positions (position zero indicates gene start).

PMcomp (Hofacker et al., 2004) transfers Sankoff's idea to a lightweight energy model based on base pairs, which allows much faster computation.

We also deduced that potential piRNAs may be target specific sites in these mRNAs based on base pairing from nucleotides 2 to 21 in the piRNAs.

Taking in consideration that T ARGETRNA limits the number of reported putative interaction sites, it achieves a fairly high sensitivity at a low false positive rate, although only an alignment-like algorithm based on base pairing potential is used.

The different local (dis)similarity measures based on base-pairing probabilities, with the exception of rmin(P, P*), correlate with each other (see Fig. 1).

MiRNAs direct cleavage or translational inhibition of a specific messenger RNA (mRNA) based on base-pairing complementarity between the miRNA and the target mRNA.