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These highly similar duplicate regions pose significant issues for some methods of automated ortholog/homeolog classification based on average sequence similarity or evolutionary distance.
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Both F* and D rely on estimation of the difference between an estimate of θ based on average pairwise sequence divergence and another estimate based on the number of segregating sites (singletons for F*, global estimate for D), whereas D* compares two estimates of numbers of segregating sites (common versus singleton).
Polymorphism levels were summarized by the estimators Theta(pi) and Theta(s), which are based on average number of pairwise sequence differences and on the number of segregating sites, respectively.
The comparison between sequence length categories based on average coverage, before and after the contig filtering step, revealed that this procedure was able to sensibly reduce the amount of short sequences, especially those shorter than 500 bp, moving the distribution of contig length towards longer and more reliable sequences.
Prices based on average energy consumption.
The coalescence time estimate based on the average sequence divergence of the 213 U5 mitochondrial genomes is approximately 25 30 ky (Table 1).
We concluded that the φ6 populations evolved under low multiplicity showed greater genetic variability than the high MOI populations, on average, based on sequence data representing ~10% of the viral genome.
Genetic distances were calculated in the same way as for the cartography of inter-individual genetic distance (see above) and were thus based on DNA sequence mismatches averaged over the four polymorphic loci (i.e. averaged p-distances over loci) computed with SPADS [ 113].
Suppose that ({X_{n},ngeq1}) is a moving average process based on a sequence ({ Y_{i},-infty< i
However, analysis of raw sequencing reads obtained from trace archives for several fungal genomes revealed that telomeric sequences occur in greater abundance than would be expected based on the average depth of sequence coverage.
The best cluster representative was identified based on sequence length and average quality values.
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