In this context, SNPs identified by means of high-throughput genotyping based on array technology could be a useful tool [ 23, 24].
This has led to the development of mutation screens based on arrayed primer extension technology, which enable the simultaneous detection of multiple mutations from one individual.
Although, the present database consisting of expression data for over 100,000 samples from five platforms covering three species (human, mouse and rat) is all from Affymetrix expression array chips, the methodology is truly platform independent and it is a straight forward matter to include data based on other array technologies.
In this paper, we describe the development of a molecular detection system, based on DNA array technology, for rapid and efficient detection of these vascular wilt pathogens.
In brief, the assay is based on digital array technology [ 3] and uses the Tau5 monoclonal antibody for capture (Covance, Princeton, NJ, USA) and HT7 and BT2 monoclonal antibodies for detection (Pierce, now part of Thermo Fisher Scientific Inc., Waltham, MA, USA).
Customer tool kits based on gate-array technology offer the four major capabilities described earlier.
The fluorescent microsphere immunoassay is based on fluidic, particle array technology (Luminex Corp., Austin, TX) and has become increasingly standardized and accepted in applications involving the serologic diagnosis of autoimmune and animal infectious diseases [ 23, 24].
An oligonucleotide probe from the same species-specific region of the E. coli 16S gene was used as a capture probe in a novel electrochemical 16-sensor array based on microfabrication technology.
Recently, a high-throughput marker array based on DArT technology was developed for cultivated oat [ 36].
Any user data uploaded to the platform is stored in a secure disk array based on Lustre technology, which is important from the point of view of efficient computation (i.e., rapid parsing and analysis of microarray data).
