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In vertebrates cellular immunity is based on antigen recognition by αβ or γδ T cell receptors (TR) chains.
Studies on the cross-reactivity of snake venoms suggest the apparent lack of a correlation between cross-reactions and phylogeny, implying that the results obtained based on antigen recognition do not completely reflect the molecular evolution of snake venoms [ 90, 91].
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Enzyme-linked immunosorbent assay (ELISA) is a simple and rapid method based on antigen and antibody recognition and is highly specific for particular residues [67, 68].
DiscoTope [ 10] predicted antigenic determinants based on antigen 3D structures.
Yao et al. tested predictions based on antigen protein structures.
To achieve these innovative strategies based on antigen- and antibody-specific recognition, antibodies for both common and new contaminants and pollutants, and even generic antibodies should be developed first.
We have developed a simple and highly reproducible IM protocol based on EpCAM antigen recognition [ 16].
We thus optimized the standard IM technique based on EpCAM antigen recognition.
These results support the potential use of H and VA as an adjunt for immune intervention in cervical cancer patients whenever clinical protocols based on tumor antigen recognition is desirable, such as in those cases where the application of E6 and E7 based therapeutic vaccines is used.
Other strategies based on antibody-antigen recognition with fluorescence and microgravimetric techniques for analyses of MTB were reported recently [13].
Astronomo, R. D. et al. A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120.
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