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This may explain why laboratory strains considered to be tachyzoites based on antigen expression differ greatly in their replication rate and capacity to form bradyzoites.
The advantage of a serological classifier over that based on antigen expression data by flow cytometry is that these data and methods are accessible for virtually all clinical facilities and are easily standardized.
A categorization of GABAergic non-pyramidal cells in the neocortex based on antigen expression revealed overlapping expression patterns between the different subgroups of neurons (Kawaguchi and Kubota 1993, 1997; Kubota et al. 2011; see also Gentet 2012).
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DiscoTope [ 10] predicted antigenic determinants based on antigen 3D structures.
Yao et al. tested predictions based on antigen protein structures.
While important to select a cancer cell-specific antigen, the prediction of total efficacy of ADCs based on the antigen expression level remains elusive (Damelin et. al., 2015).
Affinity-based enrichment distinguished cells are based on specific antigen expression methodologies, where the target cells are either labeled with a fluorescent/magnetic bead tag or directly captured on a stationary substrate.
Immunotherapeutic approaches are being developed based on antigen-specific T lymphocytes, such as antigen vaccination or adoptive T-cell transfer.
Based on cell surface antigen expression, we isolated endothelial precursor cells from bone marrow, peripheral blood and tumour-infiltrating cells from mice that had received six human breast cancer xenografts.
They described bipotent human mammary epithelial progenitor cells based on the expression of epithelial-specific antigen (ESA), sialomucin 1 (MUcommonommon acute lymphoblast antigen (CALLA/CD10), and α-integrin, in combination with exclusion of rhodamine dye.
Development of plague vaccines based on the expression of protective antigens of Y. pestis in live carriers began in parallel with the testing of subunit vaccines.
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