It has been suggested that bipolar disorder associated with migraine might represent a more severe variant of bipolar disorder, based on an earlier onset of the bipolar disorder and greater social impairment [ 36, 37].
The AD cases were divided into an early-onset (EOAD) group and a late-onset (LOAD) group based on an age-of-onset of 70 years [ 27, 29].
Based on an univariate analysis, onset of cardiovascular toxicity was significantly associated with deeper coma (p = 0.04), reduced PaO2/FiO2 ratio (p = 0.004), onset of acute renal failure (p = 0.02), requirement of mechanical ventilation (p = 0.02) and fatality (p = 0.04).
When using the DSM-IV-TR criteria instead of ICD-10, there were three cases who were given another third position code in DSM-IV-TR based on an age of onset above 18 years of age.
Two time periods of RRV notification data were included in the study based on a date of onset: the most recent outbreak year from July 1, 2011 to June 30 , 2012and the 10 years from July 1 , 2002to June 30 , 2012
The idea was based on an experimental finding that the onset potential of the PtSn for CO oxidation was lower than that of the PtRu and the resultant expectation that there seemed to be a possibility of using the PtSn as a CO filter.
Based on a published report suggesting an onset of H2BE expression prior to NeuroD, the reviewers express the important concern that our H2be:Flag-H2be transgene may not fully recapitulate the endogenous H2be expression and that the endogenous gene may be initiated at an earlier developmental stage than described in our manuscript, which would potentially invalidate some of our conclusions.
The optimal strategy varied by region and year of disease onset, based on a 25 year vineyard lifespan.
A diagnosis of unstable angina was based on a negative troponin test, new onset angina (<2 months) of at least Canadian Cardiovascular Society Classification class III, prolonged (>20 minutes) rest angina, recent (<2 months) worsening of angina, or angina that occurred within 2 weeks of a previous MI [19].
Underlying conditions were defined as conditions preceding the listeriosis onset based on a retrospective medical chart review.
