Sentence examples for based on alterations to from inspiring English sources

The metaplasia-dysplasia-carcinoma sequence, the most significant and frequent type of gallbladder carcinogenesis, is based on alterations to the epithelium of the gallbladder mucosa.

These discoveries paved the way for the synthesis of insulin and the eventual development of new forms of rapid- and protracted-acting insulin preparations based on alterations to the structure of the insulin molecule itself (insulin analogs).

However, in our study, age had no clear influence on the accuracy of the estimation of the degree of acidosis based on alterations in posture/ability to stand and was therefore not considered to be of clinical relevance.

Since bicarbonate requirements were mainly based on alterations in posture/ability to stand, the success of therapy was evaluated with regard to categories of this parameter.

Such individual differences in stress vulnerability are based on alterations in neural circuits/mechanisms designed to properly tune and terminate stress responses.

Still, of all the various psychiatric disorders, fear and anxiety are probably the most tractable scientifically because they are based on alterations normal brain functions that are beginning to be well understood.

Other attempts to increase fixation based on alterations of thread design could theoretically be achieved by increasing the number of threads being used.

Although mechanisms of alcoholism remain to be elucidated, the molecular hypothesis postulates that that alcohol dependence and toxicity result from neuroadaptations to chronic alcohol consumption based on alterations in gene expression.

This methodology has been previously utilised to predict perioperative infectious complications based on alterations in T cell pathways [ 10].

The clearest of these is the increasing incidence and prevalence of multiple sclerosis in Canada, which has resulted in a near tripling of multiple sclerosis over the last 3 generations based on alterations in the sex ratio, an effect largely limited to females (9).

DNA was amplified, and the resulting concentrations were converted to relative lesion frequencies per 10 kb DNA, based on alterations in amplification efficiency (Ayala-Torres et al. 2000).