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Only one RCT reported primary analysis based on all randomised cases 20 while the rest did not report intention to treat.
Evaluation of safety was based on all randomised patients who had received at least one dose of study drug and had at least one follow-up assessment.
The safety analysis will be based on all randomised patients who were treated with any of the interventions under investigation.
Therefore, an additional 12 patients were recruited to safeguard the power of the trial and an intention-to-treat analysis was performed based on all randomised patients.
The statistical evaluation of HbA1c, FPG and hypoglycaemic episodes was based on all randomised participants following the intention-to-treat principle.
Similar(55)
This low-viscosity cement was found to be catastrophic based on a randomised clinical study using radiostereometric analysis (RSA) [4] and 5 years of data from the Norwegian Arthroplasty Register [5].
None of the primary studies reviewed was based on a randomised design.
These findings were based on a randomised controlled trial of 11 journals published by the American Physiological Society.
The current study is based on a randomised controlled trial with a rigorously developed dipstick algorithm and clinical score.
Such studies should also be based on a randomised clinical study design and include both placebo or control groups.
Since the data was based on a randomised intervention, the possibility that the intervention had an effect on GDM incidence cannot be denied.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com