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Suitable tools (e.g. based on additive models, splines, random fields, spatial processes) have been developed, but their use is restricted in general to academia.
Our preliminary analysis based on additive models replicates prior studies to the extent that we find that indicators linked to economic and social modernization have beneficial effects on infant mortality.
All p-values are based on additive models for the genetic variants.
Rothman's model of synergism is based on additive models and was recommended in a review on how to evaluate interaction by Hallqvist et al. [ 19].
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BMI, body mass index; CAD, coronary artery disease; CI, confidence interval; OR, odds ratio; a Expected odds ratios estimated based on additive interaction models.
Despite the extensive study of the proportional hazards model for survival data with high-dimensional covariates, a few authors have utilized variable selection methods based on additive risk model which may provide more insights beyond the proportional hazards model analysis [ 4, 13].
The research in [ 17] is based on additive noise model.
Three variable selection techniques of Lasso, SCAD, and SICA were implemented on microarray gene expression data of 86 leukoplakia samples of OPL patients based on additive hazards model.
Analyses based on additive and dominant models gave similar results (Supplementary Materials 1 8).
These analyses were based on additive, recessive and dominant models, and adjusted for age, gender and BMI.
Thus we applied the departure-from-additivity model that is based on additive disease rates [42], [43].
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