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Relationship between weight loss of P 3HB-co-4HB) and relative density of hydrolysis sP 3HB-co-4HBB-co-4HB) was constructed based on Additional file 1: Figure S2a and b.
Based on Additional file 4, all MetMon+ subjects had glucose testing and 80% of those also had lipid testing.
The list is based on Additional file 3: Tables S3 and Additional file 4: Table S4 for genes with unambiguous annotations.
The IGR containing this riboswitch is 191 nucleotides long and 22.5% GC (ranked 121st in the genome based on Additional file 1).
We classified the phenotypes based on Additional file 6 and further confirmed by in situ staining using different molecular markers at different stages (Additional file 8).
To maintain an adequate number of genes for testing and a moderate correlation with the driver, we select a threshold of correlation coefficient based on Additional file 1: Figure S4 such that the number of target genes is around 100.
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The experimentation dataset is based on Additional files 1, 2, 3, 4, 5 and 6.
Additional primers were designed from RNA-Seq data for the selected DEGs based on DiffKAP (Additional file 15: Table S12).
We identified 109 SNPs with pharmacogenomic relevance based on PharmGKB (Additional file 1: Table S10).
All major clades were confirmed as monophyletic in a larger phylogenetic framework based on ND2 (additional file 3).
Thus, correlations between extracted phosphorylation motifs and specific physiological protein functions were identified here using functional enrichment analysis based on GO (Additional file 7).
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