Sentence examples for based on active sites from inspiring English sources

It includes the classification of catalysts based on active sites and structure of active sites at the nanoscale.

Based on active site structural differences between LSS and human spermidine synthase (HSS), we screened a large dataset of compounds against modeled protein using Glide virtual screen docking and selected two best inhibitors based on their docking scores (− 10.04 and − 13.11 respectively) with LSS and having least/no binding with the human enzyme.

Faber and Kazlauskas have tried to develop a classification system for enantiocomplementary enzymes based on active site structure.

Based on active site mutations present in almost all of the vertebrate PGM5 proteins, the biocurator determined that the loss of function occurred in the vertebrate common ancestor.

A mechanism based on active-site directed inactivation of the enzyme by disulfide bond formation between the active site cysteine thiol and the sulfur atom of the heterocycle is proposed.

The helix-turn-helix is a common motif and without a global sequence similarity, an evolutionary lineage based solely on active site similarity cannot be readily established.

(A total of 13 sites were in place during the post-ANGELS period, of which 9 were in active use. The analysis below is based on the active sites).

49 Virtual screening was done with a total 6,460 molecules, 5,040 experimental and 1,447 approved molecules deposited in DrugBank, based on selected active sites into the dnaE.

Importantly, we found orthologs of CPI1 in the organisms where we predicted a pathway following a cycloartenol route based on the active sites of their ERG7 (fig. 3 and table 1).

According to features of the predicted protein sequences, the InterProScan analysis was based on the active site, the binding site, the conserved site, the domain, the family, the PTM, and the repeat.

The docking studies were performed by using the software AutoDock Tools 4.1 [57] and the grid site for docking of ligands was based on the active site prediction.