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Among the most ambitious projects is a partnership with 14 cancer centers to use Watson to help choose therapies based on a tumor's genetic fingerprints.
Rather than setting up clinical trials based on a tumor's histology, as doctors have done in the past, scientists will group patients for treatment trials on the basis of similar mutations in their tumors.
Doctors try to give survival odds based on a tumor's appearance and size, but often that is just an educated guess.
Prompt diagnosis based on a tumor cytokine/receptor profile would aid in individualizing the anticancer treatment choices for these patients.
For each patient, the oncologic treatment concept after diagnosis is based on a tumor board review, following approved standard therapies and current guidelines.
Since the comparison is based on a tumor sample, which may contains genomic aberrations that could differentially affect the performance of each technology, we investigated the coverage differences in COSMIC cancer genes.
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A cancer drug based on a tumor-killing virus has for the first time succeeded in a late-stage clinical trial, giving a lift to a technology that has long tantalized doctors and researchers.
In this study, we developed a versatile RNAi nanoplatform based on a tumor-targeting and pH-responsive RNA nanoformula.
Analogous to transcriptomic profiling, DNA methylation profiling is considered to allow the molecular classification of human malignancies and monitoring cancer progression based on a tumor-specific methylation signature [ 20].
Previously, two formulas based on a logistic tumor growth model were proposed to predict tumor cellularity with DWI and DCE.
Assessment of pathological tumor response to preoperative CCRT was based on a standardized tumor regression grading (TRG) as described by Dworak et al. [ 31].
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