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The F.D.A. approved the drug based on a trial with 449 patients, all of whom received Iclusig.
In a memo dated June 12 , 2001 an executive pointed out that no cancer drug had ever been approved rapidly based on a trial using combination therapy.
The report was based on a trial in which 412 people adhered strictly to the DASH diet for 90 days while changing their salt intake every 30 days.
Genentech applied for approval of Avastin as a treatment for metastatic breast cancer based on a trial organized by academic researchers sponsored by the National Cancer Institute.
The real test will come when the company files for approval in the US, based on a trial of 141 patients.
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Selection of the right surfactant and dose is of crucial importance to the biodegradation process, but frequently the selection process is based on a trial-and-error method.
However, the development of the material so far has been based on a trial-and-error approach, and the existing materials are far from being optimized.
The workflow stated in ISO 13849-1 2006 for designing safety-related parts of control systems (SRP/CS) is based on a trial-and-error procedure whose result could be far from an optimal solution in terms of trade-off between economic cost and safety capabilities.
Stoll et al. (1995) introduced a new approach based on a trial-and-error modeling method for the interpretation of a SP profile measured over 2D sheet structures.
In our experiments, the value of N is set as five, which is determined based on a trial-and-error method on a training image.
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