The magnitude of this increase has been observed to differ depending on whether the estimate is based on a top-down (atmospheric inversion models) or a bottom-up (process-based models; adding up independently estimated flux components) analytical approach.
Its modeling approach is based on a top-down methodology and takes into account trade information.
The global placement is based on a top-down recursive bisection framework.
This overview is derived from analyzing the I&C systems based on a top-down approach.
The proposed method is suitable for developing an agent difficult to develop based on a top-down approach alone.
The Si VNWs are realized based on a top-down approach, through the transfer of hard mask by plasma etching onto the silicon substrate.
In this study, we engineered a tyrosine motif located in the intracellular domain of S-Mpl based on a top-down approach in order to change the signaling properties of the chimera.
The selection of the modulator topology and the design of its building blocks are based on a top-down CAD methodology that combines simulation and statistical optimization at different levels of the modulator hierarchy.
A coarse-grained representation based on a top-down approach must contain information about organization of the system to shed light on biological changes or interactions.
Since our models are empirical, derived based on a top-down approach, we lack such information.
Current paradigms are based on a top-down strategy which is based on initially high dose IS treatment with a reduction in case of side-effects or complications.
