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The design of the virtual screening filters is based on a thorough evaluation of docking methods, DFG-loop conformation, binding interactions and chemotype specificity of the 138 p38 MAP kinase inhibitors from Protein Data Bank bound to DFG-in and DFG-out conformations using Glide, GOLD and CDOCKER.
Interviews are offered by invitation only and are based on a thorough evaluation of your complete application.
The synthesis was based on a thorough evaluation of the quality of the reviews included and an assessment of the conclusions regarding the association between computer work and UEMSDs and recommendations for interventions.
For each approach, the target mAb protein was independently quantified by two SP that were stringently selected based on a thorough evaluation of all candidates for stability and sensitivity.
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Based on a thorough empirical evaluation using several publicly available datasets, we show that our method is able to significantly and consistently improve retrieval results every time a new type of invariance is incorporated.
Our main contributions are (i) the development of a set of strategies for compiling scientific workflows, modeled as XML processing pipelines, into parallel MapReduce networks, and (ii) a discussion of their advantages and trade-offs, based on a thorough experimental evaluation of the various translation strategies.
Diagnosis was based on a thorough clinical evaluation of patients who had suffered from sudden onset of severe fatigue for at least 6 months, had no historical, laboratory or diagnostic evidence of exclusionary medical, neurological or psychiatric disease and fulfilled the Fukuda criteria (Fukuda 1994).
6 7 Approval and proper usage of medical tests should be based on a thorough scientific evaluation.
The relapse rate of patients who are treated based on a thorough clinical evaluation should be below 14%.
10 When a child presents with fever, the decision to commence antibiotics is based on a thorough clinical evaluation by the treating physician, supplemented by rapid tests such as a urine dipstick.
It would be useful to know the relapse rate of patients who have, instead, been selected for a given treatment based on a thorough clinical evaluation, including physical examination and laboratory results (Alvarado Score) as well as radiological exams if needed or deemed helpful.
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