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Maupin turned in fresh directions after six books, with the bitter satire of ET, Maybe the Moon, and his Gothic mystery, The Night Listener, based on a profoundly creepy tale in his own life.
The two megathrifts are based on a profoundly unsound business model in which their profits accrue to shareholders and executives and their losses accrue to taxpayers.
As for Tim Hunt, maybe the guy really was joking, but the joke was based on a profoundly sexist, outmoded understanding of how things works.
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For Mr. Blair in 2003, facing anti-war demonstrations on the streets, the decision to deploy troops alongside American forces was a profoundly risky gamble, based on a hope that the battle would end quickly and cleanly in a victory resonating as much in the ballot-box as in the historical record.
It will be a profoundly political effort based on a fictitious narrative about back taxes.
And if you know Miéville for his rousing socialist critique of J. R. R. Tolkien's "Lord of the Rings" (he has referred to Tolkien's "profoundly backward-looking reaction, based on a rural idyll that never existed"), it won't surprise you that "Un Lun Dun," a buried treasure from 2007 that recently arrived in paperback, is one of the most imaginative young adult novels of the post-Potter era.
Advertising is profoundly different on mobile devices where data display is based on a feed or card paradigm rather than a web page, which has room for ads around the edges.
We have achieved statistical discrimination in the measured F/B directional data based on a small data set of normal and malignant ovaries because the optical signatures are profoundly different in these tissues but homogeneous within each type.
Biko's profoundly simple yet powerful message calls us to return to the very essence of what it means to be human, to embrace a new consciousness, one based on an ethics of care and compassion.
"Based on a T.R.U.
Based on a pinned tweet.
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