Another limitation of changepoint detection that we are currently aware of is that it cannot detect a region with a gradually increasing or decreasing methylation level, since the algorithm is based on a model postulating that a domain is consist of data points with a single mean value with a single dispersion.
This is a new bottom-up modelling capability based on a set of postulates integrating: (i) systemic thinking where systems are effected by four types of feedback loops to be described in the paper, which include positive/negative feedback; and (ii) evolutionary thinking, where each feedback loop is associated with a "risk mindset".
The Mora-Philippot theory of fresco is based on a series of postulates which should be discussed in order to accept its validity: Roman wall paintings occasionally display depressions in coloured plaster backgrounds left by hard polishing tools, imprints made by snapping a cord against the rendering, and impressions made by fingernails [62].
This model is based on a recent work postulating the existence of Hox/ParaHox, NK, and extended-Hox clusters in the common ancestor of animals (Mendivil Ramos et al., 2012 ).
A kinetic model based on a pseudohomogeneous mechanism was postulated to describe the reaction network comprising a sequence of consecutive and parallel reaction steps.
It has been postulated based on a variety of theoretical considerations that birds use two separate sets of photoreceptors for detection of chromatic and luminance signals, the single cones and double cones, respectively [5], [6].
The increase in the rate of polymerization was postulated based on a complex formation between the growing radicals and the IL.
The protective effects of HP infection on the risk of developing EA have been postulated, based on a number of epidemiologic studies (Chow et al, 1998; de Martel et al, 2005).
We evaluate the representational constructs of the two based on a set of decomposition characteristics, and postulate hypotheses comparing the two based on theories in cognitive psychology and human factors.
It turned out his old adviser had just started a company based on an idea Fennie had postulated as an undergrad, a way to model range predictions for electric cars using a complex computational system based on artificial neural networks.
