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That would seem to conflict with the headline-grabbing analysis published on May 21, 2007 by Steven Nissen of the Cleveland Clinic, which indicated, based on a pooled analysis of Glaxo's data, that patients who took Avandia were 43% more likely to have heart attacks or strokes.
To investigate the effects of an ethinylestradiol (EE) 20 μg/drospirenone (drsp) 3 mg combined oral contraceptive (COC) administered in a 24/4 regimen (24 active tablets/4 inert tablets per cycle) for the treatment of moderate acne vulgaris, based on a pooled analysis of two identically designed US studies.
Another caveat is that the value of a general pattern based on a pooled analysis is dictated by the diversity of the representative groups.
The risk model that was used was based on a pooled analysis of three cohort studies from Preston et al (2002).
Meta-analysis of the data from several clinical trials is needed to understand the efficacy of memantine based on a pooled analysis.
The risk model that was used for these calculations was an excess relative risk model based on a pooled analysis of three cohorts, including two cohorts of women who were exposed to multiple fluoroscopy examinations (Preston et al, 2002).
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In conclusion, our current study provides the first global estimate of DR and, more important, the two sight-threatening end points (PDR and DME), based on a pooled individual participant analysis of more than 20,000 participants from 35 studies around the world.
This analysis is based on a pooled German national dataset described in detail previously [ 16].
All statistical analyses were based on a pooled dataset, including all panel waves from 1994 to 2010 to allow for trend analysis at the individual and population level.
Evidence based medicine can use a pooled analysis based on data from clinical trials and applies the model to the patient.
Based on the pooled analysis, the current study revealed a larger LGR (0.86 cm/yr versus 0.33 cm/yr) and VGR (20.96 cm/yr versus 9.48 cm/yr) and a younger age (55 years versus 69.5 years).
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