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Estimates of additional lifetime from 45 years of occupational exposure (lifetime exposure) to 1 ppm derived using he Paustenbach et al. exposure matrix and best-fitting (quadratic) models ranged from 0.020 to 0.036 per thousand, whereas corresponding estimates based on a linear dose response ranged from 1.6 to 3.1 per thousand.
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Otherwise, the expected RR for the statin dose was estimated based on a linear regression using other doses of the same statin.
The increase in brain concentration of total AF150(S) was larger when based on a linear relationship between injected dose and brain concentration.
"At the very least it suggests that low-dose effects are lesser than those predicted from high-dose extrapolation based on a linear model".
The blue line displays the ROC analysis based on a linear combination of the HVLT scores.
The red line displays the ROC analysis, based on a linear combination of auditory dominance and multisensory gain.
Based on a linear regression model, it drops about 3.5% for each typo noticed.
The estimated EOR/Gy for hypothyroidism was 0.34 (95% CI: 0.15, 0.62) based on a linear dose response model.
Figure 2 shows good agreement between the ERR mortality estimates for all malignant neoplasms excluding leukaemia from NRRW-3 and the Japanese A-bomb study, based on a linear dose response model.
Brenner et al (2003) point out that based on a linear dose response, non-threshold model, 'the risk of radiation induced cancer should decrease linearly, without a threshold to arbitrarily low doses' (Brenner et al, 2003).
Because our exposure estimates for air pollution are continuous, we estimated an RR for each survey participant based on a linear dose response [see Supplemental Material, Figure S2 (http://dx.doi.org/10.1289/ehp.1103806)] for the range of observed air pollutant concentrations and the referent exposure levels described below.
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