The paper deals with a feasibility study of a space nuclear reactor for planet settlements, based on a "Generation III+" technology, specifically the integral type PWR one, currently under study in several projects (e.g. IRIS, CAREM, IMR, SMART) for its simplicity, compactness and cost reduction, but mainly based on already proven technology.
The router itself is realized as a MPSoC, where every CAN port is served by its own CIS based on a Nios II softcore CPU.
A detailed analysis based on a Swerling II target model in terms of target detection probability is presented to validate the use of PMP.
The product is already approved in 31 countries based on a phase II study (BAP00003 1) and a phase III study (BAP00089 2).
The treatment regimen was based on a phase II study, which demonstrated activity of docetaxel and irinotecan in patients with recurrent ovarian cancer (Mäenpää et al, 1999).
We cannot fully exclude that the negative findings are based on a type II statistical error; however, the study was powered on results from a previous positive study [ 8].
Based on a phase II result of MetMab, a c-Met specific antibody, patients with c-Met overexpression would benefit from Met-targeted therapy, suggesting that detection of c-Met status is critical for Met-targeted therapy.
Tests of significance and partitions of variance components for the RIL, year and RIL × year effects were carried out based on a Model II ANOVA, where the RIL and year effects were treated as random variables (Sokal and Rohlf, 1981).
A previous exploratory exposure response analysis based on a phase II clinical study in TKR subjects identified gender and AUCss as significant predictors of bleeding; however, of the variables tested in the current exposure response analysis, only daily AUCss was a significant predictor of bleeding.
Yet, the use of sorafenib in osteosarcomas is mainly based on a phase II study, conducted in 35 patients with progression despite standard treatment and reporting 5 PRs, a clinical benefit rate of 29%% and a four-month PFS of 46%% [ 25].
Implementation results based on a Virtex-II FPGA device are included.
