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Subsequent simulations were performed on a hypothetical population of 6,000 naïve individuals using a Ro of 4. In this model, isolation of patients based on a hypothetically 100% sensitive clinical case definition alone would result in 5% of the total population being infected by the end of 17 days.
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The fourth and fifth entities can either be (i) constructed hypothetically based on a user's expectations of the first three entities, or (ii) they can be empirically determined by performing the necessary analyses with the first three entities using the GATK.
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