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Further, based on a hypothesized lower sensitivity of humans to this MOA, prior reviews have concluded that rodent hepatocarcinogenesis by PPAR-α agonists is irrelevant to human carcinogenic risk.
Then, based on a hypothesized recessive trait and on the known parental consanguinity, we selected non-synonymous variants in coding regions and splice-site junctions that were homozygous in II-1 and absent or heterozygous in II-3.
Based on a hypothesized cleavage of the middle ring of norathyriol, this study was designed to determine phenolic cleavage products in the feces of pigs fed an extract of C genistoides.
Current service life models for predicting the time to chloride-induced corrosion initiation of steel reinforcement in concrete structures are based on a hypothesized surface chloride concentration, Cs, as a boundary condition.
Our initial sample size calculation was based on a hypothesized difference of 30% (between the frequencies in each group) as clinically significant and an α-error of 0.05.
The sample size calculation is based on a hypothesized 10%% improvement of the primary outcome measure back beliefs of LBP patients (measured using the Back Beliefs Questionnaire).
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Therefore, based on a clinical perspective, we hypothesized that the higher dropout rates in BED group could be related to the lack of weight lost while on treatment as many BED were found to be overweight or obese [ 22] and dieting while in treatment was not allowed.
Subsequently, we developed a further dispensation order (5′-CAGTGATAG-3′) based on the hypothesized nucleotidic change capable to better characterize the alteration identified.
This design was hypothesized based on a morphological conversion according to the assessment of thermodynamic equilibrium calculated by the contact angle measurements.
Of further interest is the fact that these findings are based on a panel of SNPs in hypothesized cancer susceptibility genes.
Based on a number of observations, we hypothesized that type I NPF release is required for nucleation, and that tight binding of the type I NPF can slow the final activation step.
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