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Software for gene-set enrichment analysis for GWAS, CNV and other genome-wide study designs, based on a genomic, interval-based permutation scheme (Lee et al., 2012).
Genomic equivalents (GE) were estimated based on a genomic size of 4,659,275 bp, the average genome size of two L. interrogans strains [ 13, 14].
Another predicted advance, though not so immediate, is that of personalized medicine -- treatment and preventive programs that are tailored to the individual based on a genomic analysis.
I will show how structural variants can be used to discover the molecular basis for more complex neurocognitive disease based on a genomic hotspot model of rare and recurrent copy number variants (CNVs).
The amount of calibrator (GE/µl) was estimated based on a genomic size of 4.659 Mb for L. interrogans serovar Lai strain Lai [23].
The Functional categories used are based on: A Genomic Perspective on Protein Families [ 82].
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Additional information about the putative gene functions was obtained from recently sequenced tomato and potato genomes, as compared to the previous annotation solely based on A. thaliana genomic information.
The reversed positions of the Ensete/Musella clade and Australimusa/Callimusa clade in the phylogenetic trees suggest that phylogenetic reconstruction based on a single genomic locus (ITS) may lead to inconsistent phylogenetic inference.
Early studies have mainly focused on pairwise comparisons based on a single genomic data type.
In another simulation by Villanueva et al. (2005), accuracies of predictions based on a realized genomic relationship matrix were greater than accuracies of predictions based on pedigree and phenotype.
Once established, the database routine can seamlessly extend the range of data queries to include statistics based on a broader genomic region, rather than a single base-pair location.
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