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Thus, substrate specificity should be based on a conserved shape rather than a particular amino acid sequence.
Not surprisingly, most RGA genes in the same family could be clustered into a single HG based on a conserved feature.
SOX genes belong to the High Mobility Group (HMG) superfamily and encode transcription factors which can be identified based on a conserved motif within the HMG domain, RPMNAFMVW [ 5].
Similarly the MCT1/2c and MCT2/1c C-terminal chimaeras were based on a conserved YRL (Tyr-Arg-Leu) sequence one residue downstream of the end of TM12 for both MCT1 and MCT2.
They are grouped based on a conserved set of distinct structural motifs.
A fourth peptide designated B138 was based on a conserved region of HIV-1 envelope.
Similar(30)
Four primers were designed to recognize six distinct regions on the target DNA based on a highly conserved sequence in the VP2 region of the BPV genome.
Four primers were designed to recognize six distinct regions based on a highly conserved sequence in the VP7 region of the rotavirus genome.
Rather, the formation of the XY body is based on a highly conserved mechanism which silences all regions of unpaired chromatin in meiotic prophase, named meiotic silencing of unsynapsed chromatin (MSUC) [19], [20], [21], which is not male-limited and probably predates the evolution of the heterologous XY pair in mammals [29].
The real-time PCR primers and probes were designed based on a highly conserved region of the SCSMV CP sequences.
The other primer is based on a universally conserved region (E. coli positions 1392 to 1406) and incorporates a 40-base GC clamp (5'-CGCCCGCCGCGCCCCGCGCCCGGCCCGCCGCCCCCGCCCCACGGGCGGTGTGTAC-3').
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