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Power calculation estimated a need for including 100 patients in each model, based on a beta of 0.90, an alpha of < 0.05 and SD=4.3 in SI.
The random effects negative binomial model allowed the overdispersion parameter to vary randomly by cluster based on a beta distribution (using the xtnbreg command in Stata) [ 24].
MethylMix is based on a beta mixture model to identify methylation states and compares them with the normal DNA methylation state.
This test is based on a beta binomial sampling model that takes into account both, the intra-library and the inter-library variability, thus identifying 'common patterns' of SAGE transcript tag changes systematically occurring across samples [ 18].
The random effects negative binomial model was used where the overdispersion parameter was allowed to vary randomly by cluster based on a beta distribution (using the xtnbreg command in Stata) [ 19].
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This problem is solved by the integrated signal-noise decomposition based on a beta-uniform mixture model of our approach.
Finally, we show that in situations where probabilistic clustering retains false positive SNVs (for instance due to insufficient sample diversity or systematic errors), applying a strand bias test based on a beta-binomial model of forward read distribution can improve precision, with negligible cost to true positive recall.
Compared with conventional dictionary learning methods, the introduced dictionary learning method is based on a popular beta process factor analysis (BPFA) for an adaptive learning performance.
Based on a hierarchical beta-binomial model, Baggerly et al. [ 21] introduced a statistic test, t w, for two-group comparisons.
Computer simulations were performed based on a bivariate beta-distribution [ 33] to examine which difference in MSD values between two association mapping methods could be expected purely by chance [ 20].
However, unlike SQN and SWAN, BMIQ is based on an explicit beta-mixture modeling framework, and uses state-membership probabilities under this beta mixture model to reassign the quantiles of the type2 probes according to the type1 distribution.
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