Sentence examples for based mutation detection methods from inspiring English sources

Detection of KRAS mutations has often been the primary validation for many of the numerous polymerase chain reaction (PCR) based mutation detection methods.

We conclude that sequencing based mutation detection is a valuable method to identify induced mutations at large.

Finally, large genomic rearrangements which will not be identified by PCR-based mutation detection methods are known to occur in BRCA1 and BRCA2.

Traditional PCR-based mutation detection methods such as single strand contamination polymorphism (SSCP) analysis would miss these mutations since only the normal allele would amplify.

In addition to rapid identification, sequencing based mutation detection also offers simultaneous mapping of these mutations.

A novel RNA-templated single-base mutation detection method based on T4 DNA ligase and reverse molecular beacon (rMB) has been developed and successfully applied to identification of single-base mutation in codon 273 of the p53 gene.

A novel PCR-based mutation detection method has been developed by Transgenomic.

179, 180 SSCP is a simple PCR-based mutation detection method.

The present data was derived from a limited number of studies, however, and may contain unintended bias based on mutation detection methods, study design or uncontrolled confounders.

Concerns with tumour heterogeneity underscore the importance of using highly sensitive mutation detection methods.

Since the sensitivity of mutation detection methods is not complete, some mutations may have remained undetected in the present study.