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The ANN based models would be quite useful in establishing relationship between these factors on the pedestrian gap acceptance behaviour at midblock crosswalks under mixed traffic conditions.

One step that large-scale agriculture could take towards adopting the nature-based model would be to shift to carbon-reducing agriculture.

By applying game-theory, Kung and Zhong [32] investigate three pricing strategies and conclude that adopting a membership-based model would be more profitable than the others.

Furthermore, a comprehensive cost comparison of an ED-based model versus non-ED-based model would be warranted.

Motivated by recent advances in high-throughput sequencing and lagging of the current structure determination pipelines, a sequence-based model would be invaluable to advance our understanding of protein motion and flexibility.

Generation of data needed to begin validation of a large rule-based model would be a resource-intensive undertaking and one that ideally would involve not only use of multiplex data to estimate model parameter values but also carefully designed experimental tests of model predictions.

We did not test whether the performance of the rule-based model would be improved if we refined classification rules using statistics from the UCI data because these data were limited to only three subjects who were indoors 87% of the time and had non-representative outdoor walking data.

The study of the clinical relevance using alternative methods (split method, minimum support etc). in the tree based model would also be interesting, but it requires a larger clinical database.

The dynamin [ 43] based model would involve the catalytic interface, if the subunits were closer.

The implementation of the proposed multi-layered methodology to any regular grid based 2D model would be straightforward.

Otherwise, if the predicted UOP was within the accepted range of target settings, the infusion rate computed from the base rate model would be retained: (9 where Lower_Limit and Upper_Limit were the lower and upper limit value of the target UOP.

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